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癌症診斷及光動力療法的新型藥物

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DEPARTMENT :	化學系 Novel Drug for Cancer Diagnostics and Photodynamic Therapy 癌症診斷及光動力療法的新型藥物
PRODUCER :	黃嘉良教授
PROJECT YEAR :	2020
LENGTH :	4 min.
ACCESS :	Open to all
SUMMARY :	光動力療法是一種已知的癌症治療方法──可以利用特定波長的光照射人體內的感光劑，以激活感光劑並破壞特定的癌細胞。尤其可應用於治療皮膚癌、前列腺癌和膀胱癌等癌症。目前，只有少數用於光動力療法的感光劑藥物得到美國FDA認證或正進行臨床試驗。有鑑於種種對感光劑改進的需求，例如對癌細胞特異性、光穿透深度和安全性方面等，黃嘉良教授與他的研究團隊發明了專門針對癌細胞的新一代感光劑藥物。該感光劑是具有特定官能團的卟啉-鑭系元素配合物，可以與特定的肽結合以增加對癌細胞的特異性。該藥物是相對安全，因為它能在較低的光能量下使用。它具有高特異性和對破壞癌細胞的選擇性。因此，它不會在治療期間和之後對患者產生不良影響。此外，該藥物還可以配合磁力共振掃描（MRI），用於早期疾病診斷。因為它可以用作造影劑以提供高分辨率圖像來準確診斷癌症。
LINK :	http://kto.hkbu.edu.hk/

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