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經過改良後的黃連解毒湯可治療阿爾茨海默病

1852

DEPARTMENT :	中醫學院
PRODUCER :	李敏教授
PROJECT YEAR :	2014 – 現在
LENGTH :	5 min.
ACCESS :	Open to all
SUMMARY :	中醫藥歷史源遠流長，博大精深，中草藥的處方、功效和用法變化萬千。自古至今，很多中醫中藥為人熟識，比如：黃連解毒湯原載于唐代的《外台秘要》，由黃連、黃柏、黃芩、梔子組成，是中國古代的清熱解毒涼血良方，甚至連日本漢方醫學界亦採用此方治病。近年來文獻資料顯示，黃連解毒湯具有明顯的抗炎、抗腦缺血、抗腫瘤、降血脂、減輕肝損害等作用。上世紀對黃連解毒湯的臨床研究主要集中在腦血管病變和精神疾病領域，進入21世紀以後，黃連解毒湯的應用幾乎擴展到全身各個系統的病變中。香港浸會大學中醫藥學院李敏教授的研究團隊發現黃連解毒湯在細胞模型上能夠清除 Aβ 蛋白和tau蛋白的聚集，在阿茲海默症的轉基因老鼠的腦部我們也發現它能夠清除 Aβ 蛋白的聚集和tau蛋白的聚集，它能夠穿過血腦屏障來清除這些導致阿茲海默症的主要的病理蛋白的聚集。李教授的團隊對黃連解毒湯的複方研究和改造，為阿茲海默症病患者帶來了新的曙光。這項嶄新的科研成果已於中國及香港申請專利並於美國獲得專利。
LINK :	http://kto.hkbu.edu.hk/

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