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納米囊泡可改善慢性病藥物的穩定性和功效

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DEPARTMENT :	中醫藥學院 Nano-vesicles for Improving Drug’s Stability and Efficacy to Treat Chronic Diseases 納米囊泡可改善慢性病藥物的穩定性和功效
PRODUCER :	楊智鈞博士
PROJECT YEAR :	2020
LENGTH :	6 min.
ACCESS :	Open to all
SUMMARY :	糖尿病和哮喘是常見的慢性疾病。由於現時仍未有方法可以完全根治糖尿病和哮喘病，患者只能暫時利用藥物來降低發病機率和舒緩發病時所帶來的痛楚。但是，糖尿病和哮喘藥物會被人體迅速代謝，當中活性藥物成分的藥效只能持續很短的時間。此外，患者可能需要服用較高劑量的藥物，以抵消藥物成分在到達身體目標部位之前的流失。有見及此，楊博士及他的研究團隊研發了一種新的技術，透過製備固態脂質囊泡來有效地包裹著藥物及作為藥物傳遞系統，可以控制藥物活性物質在體外和體內的釋放速度。這脂質囊泡可以保護及載著藥物到身體局部位置，然後以適當速度釋放出藥物活性物質。這既達到更好的藥物傳遞效果，又可增加藥物的有效作用時間和穩定性，繼而減少藥物的劑量、副作用及毒性。
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